In the series opener on Monday, May 22, Jose Ramirez and the Cleveland Guardians (20-26) square off against Luis Robert and the Chicago White Sox (19-29). The first pitch will be thrown at 6:10 PM ET at Progressive Field.

The favored Guardians have -120 moneyline odds to win against the underdog White Sox, who are listed at +100. The over/under is 8.5 runs for this contest.

Guardians vs. White Sox Time and TV Channel

  • Date: Monday, May 22, 2023
  • Time: 6:10 PM ET
  • TV: BSGL
  • Location: Cleveland, Ohio
  • Venue: Progressive Field
  • Probable Pitchers: Hunter Gaddis - CLE (0-0, 0.00 ERA) vs Jimmy Lambert - CHW (2-1, 6.23 ERA)

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Guardians vs. White Sox Betting Odds, Run Line and Total

Here's a look at the odds, run line and over/under for this matchup listed on individual sportsbooks.

Guardians Moneyline White Sox Moneyline Run Line Total
DraftKings -125 +105 - 8.5 Bet on this game with DraftKings!
BetMGM -120 +100 - 8.5 Bet on this game with BetMGM!
PointsBet -125 +105 - 9 Bet on this game with PointsBet!
Tipico -125 +105 Guardians (-1.5) - Bet on this game with Tipico!

Have the desire to wager on the Guardians' matchup against the White Sox but aren't sure where to start? We're here to assist you. Wagering on the moneyline, run line, and total are a few of the most common ways to place bets. A moneyline bet means that you think one of the teams -- for example, the Guardians (-120) -- will win the contest. Pretty simple. If you bet $10 on the Guardians to defeat the White Sox with those odds, and the Guardians emerge with the victory, you'd get back $18.33.

There are tons of other ways to bet, including on player props (will José Ramírez get a hit?), parlays (combining picks from multiple games to multiply your winnings), and more. Check out the BetMGM website and app for more details on the multitude of ways you can play.

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Read More About This Game

Guardians vs. White Sox Betting Trends and Insights

  • The Guardians have won 12, or 48%, of the 25 games they've played as favorites this season.
  • When playing as moneyline favorites with odds of -120 or shorter, the Guardians have an 11-13 record (winning 45.8% of their games).
  • The oddsmakers' moneyline implies a 54.5% chance of a victory for Cleveland.
  • The Guardians have a 1-2 record over the three games they were favored on the moneyline in their last 10 matchups.
  • In its last 10 outings (all 10 of them had set totals), Cleveland and its opponents combined to hit the over five times.
  • The White Sox have won in seven, or 25%, of the 28 contests they have been named as odds-on underdogs this year.
  • This season, the White Sox have come away with a win five times in 24 chances when named as an underdog of at least +100 or worse on the moneyline.
  • The White Sox have played as underdogs in three of their past 10 games and won one of those contests.
  • Chicago and its opponents have combined to hit the over just once in the last 10 games with a total.

Guardians vs. White Sox Player Props

Hits O/U Total Bases O/U HR O/U RBI O/U
Hunter Gaddis - - - -

Check out all the player prop markets available for this game, including betting on players to get a hit, go deep, or pick up a bunch of strikeouts. Head to BetMGM for the latest odds available for the Guardians, and place your bets.

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Guardians Futures Odds

Odds MLB Rank AL Central Rank
Win World Series +5000 16th 2nd

Think the Guardians can win it all? Check out the latest futures odds for Cleveland and place your bets with BetMGM Sportsbook! Be sure to use our link for a great new user offer.

Not all offers available in all states, please visit sportsbook websites for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.