Guardians vs. White Sox Predictions & Picks: Odds, Moneyline, Spread - May 22

Monday's contest at Progressive Field has the Cleveland Guardians (20-26) squaring off against the Chicago White Sox (19-29) at 6:10 PM ET (on May 22). Our computer prediction projects a close 6-4 victory for the Guardians, so it should be a competitive matchup.

This contest's pitching matchup is set, as the Guardians will send Hunter Gaddis to the mound, while Jimmy Lambert (2-1) will take the ball for the White Sox.

Guardians vs. White Sox Game Info & Odds

• When: Monday, May 22, 2023 at 6:10 PM ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL
• Live Stream: Watch this game on Fubo!

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Guardians vs. White Sox Score Prediction

Our prediction for this matchup is Guardians 6, White Sox 5.

Total Prediction for Guardians vs. White Sox

• Total Prediction: Over 8.5 runs

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Read More About This Game

Guardians Performance Insights

• In three games over the last 10 matchups when favored by oddsmakers, the Guardians have a record of 1-2.
• In its last 10 games with a total, Cleveland and its opponents have failed to hit the over five times.
• The Guardians have not played a game with a spread over their last 10 outings.
• The Guardians have entered the game as favorites 25 times this season and won 12, or 48%, of those games.
• This season Cleveland has won 11 of its 24 games, or 45.8%, when favored by at least -120 on the moneyline.
• The implied probability of a win from the Guardians, based on the moneyline, is 54.5%.
• Cleveland has scored the third-fewest runs in the majors this season with just 164 (3.6 per game).
• The Guardians have a 3.93 team ERA that ranks ninth among all league pitching staffs.

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Guardians Schedule