Tuesday's contest at Oracle Park has the San Francisco Giants (74-70) squaring off against the Cleveland Guardians (68-77) at 9:45 PM ET (on September 12). Our computer prediction projects a close 7-6 victory for the Giants, so expect a tight matchup.

This contest's pitching matchup is set, as the Giants will send Sean Manaea (5-5) to the mound, while Cal Quantrill (2-6) will get the nod for the Guardians.

Guardians vs. Giants Game Info & Odds

  • When: Tuesday, September 12, 2023 at 9:45 PM ET
  • Where: Oracle Park in San Francisco, California
  • How to Watch on TV: MLB Network
  • Live Stream: Watch this game on Fubo!

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Guardians vs. Giants Score Prediction

Our pick for this game is Giants 7, Guardians 6.

Total Prediction for Guardians vs. Giants

  • Total Prediction: Over 8.5 runs

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Read More About This Game

Guardians Performance Insights

  • The Guardians have played as the underdog in six of their past 10 games and have gone 2-4 in those contests.
  • In its last 10 games with an over/under, Cleveland and its opponents have combined to eclipse the total five times.
  • The Guardians' previous 10 contests have not had a spread set by oddsmakers.
  • The Guardians have been chosen as underdogs in 69 games this year and have walked away with the win 29 times (42%) in those games.
  • This season, Cleveland has come away with a win two times in five chances when named as an underdog of at least +150 or longer on the moneyline.
  • The moneyline set for this matchup implies the Guardians have a 40% chance of walking away with the win.
  • Cleveland is the fourth-lowest scoring team in baseball averaging four runs per game (583 total).
  • Guardians pitchers have a combined ERA of 3.98 ERA this year, ninth-best in baseball.

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Guardians Schedule

Date Opponent Score Pitching Matchup
September 7 @ Angels L 3-2 Cal Quantrill vs Jhonathan Diaz
September 8 @ Angels W 6-3 Logan Allen vs Griffin Canning
September 9 @ Angels L 6-2 Lucas Giolito vs Tyler Anderson
September 10 @ Angels L 2-1 Tanner Bibee vs Kenny Rosenberg
September 11 @ Giants L 5-4 Gavin Williams vs Alex Cobb
September 12 @ Giants - Cal Quantrill vs Sean Manaea
September 13 @ Giants - Logan Allen vs Kyle Harrison
September 15 Rangers - Lucas Giolito vs Jon Gray
September 16 Rangers - Tanner Bibee vs Nathan Eovaldi
September 17 Rangers - Gavin Williams vs Max Scherzer
September 18 @ Royals - Cal Quantrill vs Jordan Lyles