Wednesday's contest features the Cleveland Guardians (74-84) and the Cincinnati Reds (81-77) clashing at Progressive Field in what is expected to be a competitive matchup, with a projected 5-4 victory for the Guardians according to our computer prediction. First pitch is at 6:10 PM ET on September 27.

The Guardians will look to Shane Bieber (5-6) against the Reds and Andrew Abbott (8-5).

Guardians vs. Reds Game Info & Odds

  • When: Wednesday, September 27, 2023 at 6:10 PM ET
  • Where: Progressive Field in Cleveland, Ohio
  • How to Watch on TV: BSGL
  • Live Stream: Watch this game on Fubo!

Bet on this matchup with BetMGM Sportsbook and use bonus code "GNPLAY" for special offers!

Guardians vs. Reds Score Prediction

Our pick for this contest is Guardians 5, Reds 4.

Total Prediction for Guardians vs. Reds

  • Total Prediction: Over 8 runs

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Explore More About This Game

Guardians Performance Insights

  • In seven games over the last 10 matchups when favored by bookmakers, the Guardians have a record of 2-5.
  • In its last 10 games with a total, Cleveland and its opponents are 5-5-0 when it comes to hitting the over.
  • Sportsbooks have not set a spread for any of the Guardians' last 10 games.
  • The Guardians have won 37, or 51.4%, of the 72 games they've played as favorites this season.
  • This season Cleveland has won 28 of its 57 games, or 49.1%, when favored by at least -125 on the moneyline.
  • The moneyline for this contest implies a 55.6% chance of a victory for the Guardians.
  • Cleveland has scored the fifth-fewest runs in the majors this season with just 649 (4.1 per game).
  • The Guardians have a 3.99 team ERA that ranks ninth among all MLB pitching staffs.

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Guardians Schedule

Date Opponent Score Pitching Matchup
September 21 Orioles W 5-2 Hunter Gaddis vs Grayson Rodriguez
September 22 Orioles W 9-8 Shane Bieber vs Dean Kremer
September 23 Orioles L 2-1 Cal Quantrill vs John Means
September 24 Orioles L 5-1 Triston McKenzie vs Kyle Gibson
September 26 Reds L 11-7 Lucas Giolito vs Hunter Greene
September 27 Reds - Shane Bieber vs Andrew Abbott
September 29 @ Tigers - Cal Quantrill vs Joey Wentz
September 30 @ Tigers - Triston McKenzie vs Eduardo Rodríguez
October 1 @ Tigers - Lucas Giolito vs Eduardo Rodríguez